Home > Press > The role of lipid nanoparticles and its surface modification in reaching the brain: This article by Dr. Manoli Igartua et al. is published in Current Drug Delivery, Volume 15, Issue 9, 2018
 |
Abstract:
Nanomedicine refers to field of science that uses nanotechnology for clinical operations. The use of nanoparticles (NPs) has specially been successful due to their structure. For example, NPs have the ability to cross biological barriers which boosts their effectiveness towards complicated drug delivery problems. This permeability allows NPs to reach biological targets such as brain cells, which would have been impossible by conventional drugs. Due to their effectiveness in this area, NPs have now been prioritized from simply being experimental tests compounds to be used as a workable solution for neurodegenerative disease (ND). NDs, such as Alzheimer's disease and Parkinson's disease are usually correlated with neuronal death, or in other words, the continuous structural and functional neuronal loss.
The role of lipid nanoparticles and its surface modification in reaching the brain: This article by Dr. Manoli Igartua et al. is published in Current Drug Delivery, Volume 15, Issue 9, 2018
Sharjah, U.A.E. | Posted on December 14th, 2018In common ND treatment strategies, one of the hardest obstruction to overcome is low penetration of the drug through the central nervous system (CNS). One of the reasons for this problem is the Blood Brain Barrier (BBB) and Blood Cerebrospinal Fluid Barrier (BCSFB) which protect the brain from invading and unwanted substances. The barriers carry out their function with the help of multispecific transport proteins and detoxifying enzymes. Using nanoparticles opens up many possibilities to counter such obstacles in the NDs treatment as they are proven to effectively deliver drugs to the CNS. The research focuses on the modification of lipid nanoparticles for brain targeting to increase drug efficiency and ability to deliver different kinds of drugs.
In conclusion, it has been difficult to establish which lipid nanoparticle, based on previous tests, was best for ND treatment since the administration route or animal models for each test were different. For the time being, researchers suggest that additional studies and tests are needed to propel research on CNS based drug delivery towards successful brain cell targeting.
####
For more information, please click here
Contacts:
Faizan ul Haq
Copyright © Bentham Science Publishers
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Closing the gaps MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Cancer
The mechanism of a novel circular RNA circZFR that promotes colorectal cancer progression July 5th, 2024
Possible Futures
Closing the gaps MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Nanomedicine
Multiphoton polymerization: A promising technology for precision medicine February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
SMART researchers pioneer first-of-its-kind nanosensor for real-time iron detection in plants February 28th, 2025
Discoveries
Closing the gaps MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Announcements
Closing the gaps MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Leading the charge to better batteries February 28th, 2025
Quantum interference in molecule-surface collisions February 28th, 2025
New ocelot chip makes strides in quantum computing: Based on "cat qubits," the technology provides a new way to reduce quantum errors February 28th, 2025
Nanobiotechnology
Multiphoton polymerization: A promising technology for precision medicine February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
SMART researchers pioneer first-of-its-kind nanosensor for real-time iron detection in plants February 28th, 2025
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||