Home > Press > Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs
Abstract:
Iranian researchers produced anti-breast-cancer drug by using Artemisia annua plant.
Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs
Tehran, Iran | Posted on August 29th, 2015The drug has been produced and analyzed at laboratorial scale, and it has successful effects in reducing the size of breast cancer tumors in animal samples.
Artemisinin is the active pharmaceutical ingredient (API) of Artemisia annua plant. Artemisinin has more toxicity on cancer cells in the presence of iron and transferrin. In this research, targeted magnetic nanoliposomes containing artemisinin and holo-transferrin were produced and in-vitro studies were carried out on their anticancer effect on breast cancer cells (MCF-7). In-vivo studies were also carried out on mice suffering from breast cancer.
Based on the results, the functionalization of nanoliposomes with magnetic iron nanoparticles facilitates drug delivery to the tumors. In addition, a significant increase is observed in the efficiency of the entrapped drug in the elimination of breast tumor in the sample animals.
According to the researchers, magnetic nanoliposomes containing artemisinin and transferrin were produced in this research through extrusion method, and some of their physical and chemical properties were studied. Next, in-vitro studies were carried out on the toxicity of the produced nanoliposomes through MTT method on MCF-7 cancer cells.
Results showed that the amount of artemisinin and transferrin in the tumor increased 10 and 5.5 times respectively in comparison with the complex created with the free form of the drugs two hours after the injection of magnetic nanoliposomes containing medication in the presence of magnetic field. In addition, the tumor volume in the sample mice significantly reduced in 15 days due to the presence of the magnetic field.
Results of the research have been published in PHARMACOGNOSY MAGAZINE, vol. 11, issue 42, 2015, pp. 117-122.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Researchers develop molecular qubits that communicate at telecom frequencies October 3rd, 2025
Next-generation quantum communication October 3rd, 2025
"Nanoreactor" cage uses visible light for catalytic and ultra-selective cross-cycloadditions October 3rd, 2025
Cancer
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
Ben-Gurion University of the Negev researchers several steps closer to harnessing patient's own T-cells to fight off cancer June 6th, 2025
Self-propelled protein-based nanomotors for enhanced cancer therapy by inducing ferroptosis June 6th, 2025
Nanomedicine
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
New imaging approach transforms study of bacterial biofilms August 8th, 2025
Cambridge chemists discover simple way to build bigger molecules – one carbon at a time June 6th, 2025
Electrifying results shed light on graphene foam as a potential material for lab grown cartilage June 6th, 2025
Discoveries
Researchers develop molecular qubits that communicate at telecom frequencies October 3rd, 2025
Next-generation quantum communication October 3rd, 2025
"Nanoreactor" cage uses visible light for catalytic and ultra-selective cross-cycloadditions October 3rd, 2025
Announcements
Rice membrane extracts lithium from brines with greater speed, less waste October 3rd, 2025
Researchers develop molecular qubits that communicate at telecom frequencies October 3rd, 2025
Next-generation quantum communication October 3rd, 2025
"Nanoreactor" cage uses visible light for catalytic and ultra-selective cross-cycloadditions October 3rd, 2025
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Spinel-type sulfide semiconductors to operate the next-generation LEDs and solar cells For solar-cell absorbers and green-LED source October 3rd, 2025
Rice membrane extracts lithium from brines with greater speed, less waste October 3rd, 2025
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||