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Abstract:
Scientists from Tomsk Polytechnic University and National Autonomous Mexico University develop techniques to treat diabetic foot syndrome with special insoles with silver nano-particles. The techniques help to fight ulcers appearing on feet in diabetic patients, facilitates their healing and disinfection, reducing the risk of amputation.

How to Avoid Foot Amputation in Diabetic Patients?

Tomsk, Russia | Posted on April 22nd, 2016

Silver preparations being developed by Tomsk Polytechnic University jointly with Novosibirsk and Mexican counterparts are able to reduce such risks.

“The research has shown silver’s antibacterial properties facilitate rapid healing of ulcers and suppurations in patients with diabetic foot syndrome. Together with colleagues from Mexico, where the problem is particularly acute, we are working to create special insoles for diabetic patients.

The development has passed clinical tests. In patients who had used the insoles impregnated with silver nanoparticles, foot ulcers healed up, the risk of amputations significantly reduced”:

says TPU Professor Alexey Pestryakov, Head of the Department of Physical and Analytical Chemistry.

Diabetic foot syndrome is one of the latest and most serious complications of diabetes. Due to the large amount of sugar in the body there are changes in peripheral nerves, blood vessels, skin and soft tissues, bones and joints of the patient. Infections, ulcers, suppurations and so on are emerging. Up to 15% of people with diabetes have the risk of developing ulcers on feet. In the advanced form diabetic foot syndrome can lead to amputation.

A team led by the scientist develops pharmaceuticals based on silver nano-particles having universal impact on viruses, bacteria and fungi. The scientists have cooperated with Mexican colleagues for more than 10 years.

“We have got a contract with the Mexican government, gained large grants for research. Built a serious team consisted of scientists and doctors. Together we work to improve the quality of our products, we carry out joint research and experiments”: says Prof Alexey Pestryakov.

To be noted Professor Alexey Pestryakov is one of the most cited scientists of Tomsk Polytechnic University. Conducts his research in collaboration with colleagues around the world. The professor has published over 100 scientific articles in international peer-reviewed journals, has more than 120 co-authors - leading scientists from the UK, Germany, Italy, Mexico, Spain, Portugal, Brazil, Cuba and other countries.

tpu.ru/en/news-events/801/

Full bibliographic information

Belén Borrego; Gema Lorenzo; Josué D. Mota-Morales, Horacio Almanza-Reyes, Francisco Mateos, Elena López-Gi1, Nuria de la Losa, Vasily A. Burmistrov, Alexey N. Pestryakov, Alejandro Brun, Nina Bogdanchikova, POTENTIAL APPLICATION OF SILVER NANOPARTICLES TO CONTROL THE INFECTIVITY OF RIFT VALLEY FEVER VIRUS IN VITRO AND IN VIVO, Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, DOI: 10.1016/j.nano.2016.01.021

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About Tomsk Polytechnic University (TPU)
Tomsk Polytechnic University (TPU), founded in 1896, is a leading Russia’s technical institution, which integrates research and education in the field of resource efficient technologies. In 2015 TPU has entered in the top 300 of THE World University Rankings and in the top 500 of the QS World University Rankings. Its 11 institutes include 99 departments, 66 laboratories, provide thorough training and research facilities for more than 16,000 students. TPU trains high-class engineers and encourages young scientists in nuclear and hydrogen energy, oil & gas industry, IT, power and electrical engineering, nanotechnology and biotechnology. Cutting-edge research and educational facilities made TPU a base institution for Gazprom, Rosatom and Sibur companies.

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Kristina Nabokova

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