Home > Press > Novel nanoparticles could save soldiers' lives after explosions
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| Soldiers with life-threatening blast wounds might one day benefit from a new nanoparticle under development. Credit: Stocktrek Images/iStock/Thinkstock |
Abstract:
Soldiers who suffer internal trauma from explosions might one day benefit from a new treatment now under development. Researchers report in the journal ACS Macro Letters that injecting a certain type of nanoparticle helped reduce lung damage in rats experiencing such trauma. The potential treatment, which could be given at the most critical moment immediately after a blast, could save lives.
Novel nanoparticles could save soldiers' lives after explosions
Washington, DC | Posted on April 15th, 2015Pamela J. VandeVord, Erin B. Lavik and colleagues explain that in today's conflict zones, explosions account for 79 percent of combat-related injuries. Internal bleeding in the lungs resulting from these blasts can lead to death. Soldiers with such injuries need medical attention within a few hours, but options for immediate treatment are lacking. VandeVord's team set out to fill this therapeutic void.
Building on past research in this area, the researchers paired clot-promoting nanoparticles with a corticosteroid that stops inflammation. They injected the particles in rats within 10 minutes of traumatic injury and found the therapeutic compound increased oxygen levels, and reduced internal bleeding and cellular damage in the lungs. The researchers conclude that the nanoparticles could be a good candidate to develop further for emergency trauma care.
The authors acknowledge funding from the U.S. Department of Defense and the National Institutes of Health.
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About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 158,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
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Contacts:
Pamela J. VandeVord, Ph.D.
School of Biomedical Engineering and Sciences
Virginia Tech University
Blacksburg, VA 24061
Phone: 540-231-1994
General Inquiries:
Michael Bernstein
202-872-6042
Science Inquiries:
Katie Cottingham, Ph.D.
301-775-8455
Copyright © American Chemical Society
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