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Abstract:
Reportlinker.com announces that a new market research report is available in its catalogue:

Nanotechnology in Health Care

www.reportlinker.com/p060968/Nanotechnology-in-Health-Care.html

US demand to rise more than 17% annually thru 2014

Reportlinker Adds Nanotechnology in Health Care

New York, NY | Posted on July 22nd, 2010

US demand for nanotechnology medical products will rise more than 17 percent per
year to $75.1 billion in 2014. Going forward, the increasing flow of new
nanomedicines, nanodiagnostics, and nanotech- based medical supplies and devices
into the US marketplace will boost demand to $149 billion in 2019.

Nanomedicine market to reach $59 billion in 2014

The total market for nanomedicines will command strong growth over the long
term, rising to almost $59 billion in 2014 and sustaining a strong upward pace
through 2019. Treatments based on humanized monoclonal antibodies, nanopolymers
and nanoproteins will drive gains, with compounds for cancer, heart diseases,
neurological disorders and viral infections leading new product introductions
and growth opportunities. Eventually, nanomedicines will extend into all major
therapeutic classes, encompassing numerous formulations and delivery systems.

Nanodiagnostic products to grow nearly 7% annually

Among nanodiagnostic products, nanosized monoclonal antibody labels and DNA
probes are greatly enhancing the speed, accuracy, capabilities and
cost-effectiveness of in vitro diagnostic testing, drug discovery and medical
research procedures. Nanoparticle formulations of superparamagnetic iron oxide,
gadolinium, perfluorocarbon and specialty polymers will broaden in vivo imaging
capabilities by enabling the detection of tumors, plaque, genetic defects and
other disease states at much earlier stages and with lower, safer concentrations
of injected compounds. Reflecting anticipated performance advantages over
existing products and an expanding range of new commercial offerings, demand for
nanodiagnostics is projected to increase 6.8 percent per year to $11.3 billion
in 2014, and continue rising at a good pace through 2019.

Nanotech supplies, devices to reach $5.1 billion in 2014

Within the medical supplies and devices segment, nanomaterials are already
gaining significant demand as active ingredients of burn dressings, bone
substitutes, and dental repair and restoration products. In the long term,
advances in nanotechnology will lead to the introduction of new, improved
medical supply and device coatings as well as a new, diverse group of medical
implants. In 2014, demand for medical supplies and devices based at least
partially on nanomaterials is projected to reach $5.1 billion, up from $530
million in 2009. This amount will more than triple by 2019 as
nanotechnology-based orthopedic and cardiac implants and nanocoated medical and
surgical instruments penetrate the marketplace.

Cancer among first disorders treated by nanotechnology

The greatest near-term impact of nanotechnology in health care by indication
will be in therapies and diagnostics for cancer and central nervous system
disorders. Gradually, many other major diseases, as well as injuries, will be
treated and detected routinely by products based on nanosized ingredients. The
nanotechnology segment of the medical product industry is divided among large
multinational drug and medical supply companies, and research-oriented firms
that develop commercial products or nanomaterials.

Study coverage

This new industry study presents historical demand data plus forecasts for 2014
and 2019 by product type and application. The study also considers recent health
insurance reforms and overall drug and medical device regulatory trends,
evaluates company market share and profiles participants in the US industry.

TABLE OF CONTENTS

INTRODUCTION xii

I. EXECUTIVE SUMMARY 1
II. MARKET ENVIRONMENT 4

General 4

Macroeconomic Trends 5

Demographic Patterns 8

Trends in Health Care 11

Health Insurance & Reimbursement 12

Medical Conditions 14

Chronic Conditions 15

Acute Conditions 18

National Health Expenditures 20

Medical Facilities & Professionals 24

Acute Care Hospitals 25

Physicians 25

Outpatient Facilities 26

Skilled Nursing Homes 26

Dentists 27

Patient Activity 27

Hospital Activity 29

Surgical Procedures 29

Outpatient Activity 30

Diagnostic Tests 31

Medical Products Market Outlook 32

Pharmaceuticals & Biologicals 34

Surgical Appliances & Supplies 36

Surgical & Medical Instruments 36

Electromedical Equipment 37

Diagnostic Products 37

Other Medical Products 38

III. MEDICAL NANOMATERIALS 39

General 39

Monoclonal Antibodies 41

Drug Nanoparticles 43

DNA Materials 45

Quantum Dots 47

Other Medical Nanomaterials 49

Commercialized Materials 49

Dendrimers 50

Fullerenes 51

Nanotubes & Nanowires 53

IV. NANOTECHNOLOGY HEALTH CARE OVERVIEW 54

General 54

Product Applications 55

Regulation 59

Pharmaceuticals 59

Diagnostic Products 60

Medical Supplies & Devices 61

Current Good Manufacturing Processes 62

Investment 63

US Trade Opportunities 65

International Activities 66

V. NANOMEDICINES 72

General 72

Monoclonal Antibodies 75

Types of Monoclonal Antibodies 77

Marketed Products 79

Developmental Activities 96

Nanopolymer Medicines 102

Marketed Products 103

PEG-Based Nanomedicines 104

Other Nanopolymer Medicines 107

Developmental Activities 109

Crystalline Nanomedicines 111

Marketed Products 112

Developmental Activities 115

Liposomal Nanomedicines 115

Marketed Products 117

Developmental Activities 118

Other Nanomedicines 119

Marketed Products 121

Developmental Activities 122

VI. NANODIAGNOSTICS 124

General 124

In Vitro Nanodiagnostics 126

Monoclonal Antibody-Based Nanodiagnostics 128

Immunological Reagents 129

Cellular Analysis Reagents 133

Immunohematology Reagents 134

Research Reagents 136

DNA-Based Nanodiagnostics 137

Amplified DNA Probes 139

Direct DNA Probes 141

DNA Microarrays 142

Other DNA-Based Nanodiagnostics 145

In Vivo Nanodiagnostics 150

MRI Imaging Agents 151

Marketed Products 152

Developmental Products 154

Other In Vivo Nanodiagnostics 155

VII. NANOTECHNOLOGY MEDICAL SUPPLIES

& DEVICES 157

General 157

Wound Management Products 160

Wound Dressings 161

Wound Closures 164

Bone Substitutes 165

Dental Products 168

Product Groups 169

Suppliers 170

Surgical Supplies & Devices 171

Surgical Textiles 172

Surgical Devices 173

Medical Implants 174

Orthopedic Implants 175

Cardiac Implants 178

Cochlear Implants 179

Other Medical Implants 180

Ophthalmic Products 182

Nanocoated Lenses 183

Drug Delivery Systems 184

Retinal Implants 184

Other Nanotechnology Medical Supplies & Devices 185

Catheters & Related Devices 186

Disinfectants 187

Artificial Skin 188

VIII. APPLICATIONS 190

General 190

Cancer 193

Epidemiological Trends 194

Nanomedicines 195

Nanodiagnostics 197

Nanotechnology Medical Supplies & Devices 199

Central Nervous System Conditions 199

Epidemiological Trends 200

Nanomedicines 201

Nanodiagnostics 202

Nanotechnology Medical Supplies & Devices 202

Infective Conditions 203

Epidemiological Trends 205

Nanomedicines 206

Nanodiagnostics 207

Nanotechnology Medical Supplies & Devices 208

Cardiovascular Conditions 208

Epidemiological Trends 209

Nanomedicines 210

Nanodiagnostics 210

Nanotechnology Medical Supplies & Devices 211

Other Applications 212

Ophthalmic Conditions 213

Medical Research & Drug Discovery 214

Respiratory Conditions 215

Endocrine Conditions 215

Gastrointestinal Conditions 215

Dermatological Conditions 216

All Other Applications 216

IX. INDUSTRY STRUCTURE 218

General 218

Market Share 220

Competitive Strategies 223

Licensing Agreements 225

Mergers & Acquisitions 231

Research & Development 235

Marketing & Distribution 237

Manufacturing 238

Company Profiles 239

Abbott Laboratories 240

Abraxis BioScience Incorporated 244

Access Pharmaceuticals Incorporated 246

Advion BioSciences Incorporated 247

Alexion Pharmaceuticals Incorporated 248

AMAG Pharmaceuticals Incorporated 249

Amgen Incorporated 250

Arrowhead Research Corporation 252

AstraZeneca plc 255

Bayer AG 257

BIOCIUS Life Sciences Incorporated 259

Biogen Idec Incorporated 260

Biophan Technologies Incorporated 262

BioTrove, see Life Technologies

Bristol-Myers Squibb Company 263

Calando Pharmaceuticals, see Arrowhead Research

Centocor Ortho Biotech Products, see Johnson & Johnson

Covidien plc 266

CritiTech Incorporated 267

Crystalplex Corporation 268

CytImmune Sciences Incorporated 269

Danaher Corporation 270

Dendritic Nanotechnologies, see Starpharma Holdings

Elan Corporation plc 271

Enzon Pharmaceuticals Incorporated 275

Flamel Technologies SA 278

Genentech, see Roche Holding

GlaxoSmithKline plc 280

ImClone Systems, see Lilly (Eli) and Company

Intradigm, see Silence Therapeutics

Johnson & Johnson 282

Kerr, see Danaher

Life Technologies Corporation 287

Lilly (Eli) and Company 290

Luna Innovations Incorporated 292

Merck & Company Incorporated 294

Mersana Therapeutics Incorporated 296

NanoBio Corporation 297

Nanobiotix SA 298

NanoCarrier Company Limited 299

NanoDel Technologies GmbH 300

NanoHorizons Incorporated 300

NanoInk Incorporated 301

NanoLab Incorporated 302

Nanospectra Biosciences Incorporated 303

Nanosys Incorporated 304

Nektar Therapeutics Incorporated 305

Novagali Pharma SA 309

Novartis AG 310

Novavax Incorporated 312

Orthovita Incorporated 313

Oxonica plc 314

Pfizer Incorporated 315

Pioneer Surgical Technology Incorporated 319

pSivida Corporation 320

Roche Holding Limited 321

Salvona Technologies Incorporated 329

Schering-Plough, see Merck & Company

Sensatex Incorporated 330

Siemens AG 331

SkyePharma plc 333

Smith & Nephew plc 334

Soliqs, see Abbott Laboratories

Spectrum Pharmaceuticals Incorporated 336

Starpharma Holdings Limited 338

Tego Biosciences, see Arrowhead Research

Teva Pharmaceutical Industries Limited 339

3M Company 340

Wyeth, see Pfizer

Other Companies Mentioned in the Study 341

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY

Summary Table 3

SECTION II -- MARKET ENVIRONMENT

1 Macroeconomic Indicators 8

2 Resident Population by Age Group 11

3 Health Insurance Coverage of the US Population 14

4 Chronic Conditions by Type 18

5 Acute Conditions by Type 20

6 National Health Expenditures 23

7 Selected Medical Facilities & Professionals by Type 24

8 Patient Activity by Type 28

9 Medical Products Demand by Group 33

SECTION III -- MEDICAL NANOMATERIALS

1 Medical Nanomaterials Demand by Type 40

SECTION IV -- NANOTECHNOLOGY HEALTH CARE

OVERVIEW

1 Nanotechnology Medical Products Demand by Group 58

2 US Trade in Nanotechnology Medical Products 66

3 World Demand for Nanotechnology Medical Products

by Region 68

SECTION V -- NANOMEDICINES

1 Nanomedicines Demand by Product Group 74

2 Monoclonal Antibody Nanomedicines Demand by Indication 77

3 Therapeutic Monoclonal Antibodies Approved for US Sale 80

4 US Sales of Selected Therapeutic Monoclonal Antibodies,

2004 & 2009 95

5 Nanopolymer Medicines Demand by Indication 103

6 Polymer Nanomedicines Approved for US Sale 104

7 US Sales of Nanopolymer Medicines, 2004 & 2009 108

8 Crystalline Nanomedicines Demand by Indication 112

9 Crystalline Nanomedicines Approved for US Sales 114

10 Liposomal Nanomedicines Demand by Indication 117

11 Other Nanomedicines Demand by Indication 120

SECTION VI -- NANODIAGNOSTICS

1 Nanodiagnostics Demand by Product Group 125

2 In Vitro Nanodiagnostics Demand by Product Group 127

3 Monoclonal Antibody-Based Nanodiagnostics Demand

by Type 129

4 Monoclonal Antibody-Based Immunological Reagents

Demand 130

5 Monoclonal Antibody-Based Cellular Analysis Reagents

Demand 134

6 Monoclonal Antibody Immunohematology Reagents Demand 136

7 Monoclonal Antibody-Based Research Reagents Demand 137

8 DNA-Based Nanodiagnostics Demand by Type 138

9 In Vivo Nanodiagnostics Demand by Product Group 151

SECTION VII -- NANOTECHNOLOGY MEDICAL

SUPPLIES & DEVICES

1 Nanotechnology Medical Supplies & Devices Demand

by Product Group 159

2 Nanotechnology Wound Management Products Demand

by Type 161

3 Nanotechnology Bone Substitutes Demand 167

4 Nanotechnology Dental Products Demand by Group 168

5 Nanotechnology Surgical Supplies & Devices Demand 172

6 Nanotechnology Medical Implant Demand by Type 175

7 Nanotechnology Ophthalmic Products 183

8 Other Nanotechnology Medical Supplies & Devices 186

SECTION VIII -- APPLICATIONS

1 Nanotechnology Medical Products Demand by Application 192

2 Nanotechnology Medical Products Demand

in Cancer Applications 194

3 Nanotechnology Medical Products Demand

in Central Nervous System (CNS) Applications 200

4 Nanotechnology Medical Products Demand

in Infective Condition Applications 205

5 Nanotechnology Medical Products Demand

in Cardiovascular Applications 209

6 Nanotechnology Medical Products Demand

in Other Applications 213

SECTION IX -- INDUSTRY STRUCTURE

1 US Nanotechnology Medical Product Sales by Company, 2009 219

2 Selected Cooperative Agreements 226

3 Selected Acquisitions & Divestitures 233

LIST OF CHARTS

SECTION II -- MARKET ENVIRONMENT

1 Medical Products Demand by Group, 2009 34

SECTION III -- MEDICAL NANOMATERIALS

1 Medical Nanomaterials Demand by Type, 2009 41

SECTION IV -- NANOTECHNOLOGY HEALTH CARE

OVERVIEW

1 Nanotechnology Medical Products Demand by Group, 2009 58

SECTION V -- NANOMEDICINES

1 Nanomedicines Demand by Product Group, 2009 75

SECTION VI -- NANODIAGNOSTICS

1 Nanodiagnostics Demand by Product Group, 2009 126

SECTION VII -- NANOTECHNOLOGY MEDICAL SUPPLIES

& DEVICES

1 Nanotechnology Medical Supplies & Devices Demand

by Product Group, 2014 160

SECTION VIII -- APPLICATIONS

1 Nanotechnology Medical Products Demand

by Application, 2009 193

SECTION IX -- INDUSTRY STRUCTURE

1 Nanotechnology Medical Products Market Share

by Company, 2009 223