Home > News > Nanoparticles send peptides round the twist
July 18th, 2007
Nanoparticles send peptides round the twist
Abstract:
Nanoparticles with flexible side chains cause peptides to adopt a helical form, making them promising anticancer agents.
Vincent Rotello and colleagues at the University of Massachusetts, Amherst, US, used functionalised gold nanoparticles to persuade a tetraaspartate peptide (TAP) to form an alpha-helix. In the absence of the nanoparticles, the peptide forms a random coil ("Binding and templation of nanoparticle receptors to peptide -helices through surface recognition" - free access article).
Source:
nanowerk.com
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