Home > Press > Scientists Develop Biodegradable Implants for Orthopedics Applications
Abstract:
Iranian researchers used bioceramic nanostructured materials for the modification of implant alloys and presented biodegradable implants for orthopedics, jaw and face applications.
The materials have been produced at laboratorial scale, and they increase the recovery and treatment rate of the broken bones.
Many efforts have been made in recent years to produce biodegradable implants for orthopedics, jaw and face applications to eliminate the second surgery for the removal of implants. Magnesium-based alloys have attracted the attention of the researchers in this regard. However, high corrosion rate is the most important problem in the application of these alloys, which results in the production of hydrogen and in degradation of the host tissue. In addition to improving resistance against corrosion, the coating of the alloy speeds up the bone making process in the damaged area by increasing the bioactivity.
The main objective of the research was to optimize corrosion behavior, bioactivity and biocompatibility of magnesium alloy by using diopside coating through plasma anodize/electrical sedimentation of suspended particles method. Among the applications of the achievements of the research, mention can be made of orthopedics, jaw and face surgeries to heal bone fractures by using biodegradable implants.
Results obtained from animal in vivo and in vitro biodegradability, bioactivity and biocompatibility tests showed that the diopside coating provides all corrosive, bioactivity and bio compatibility properties at the same time at optimized level for the desired magnesium alloy.
Results of the research have been published in Applied Surface Science, vol. 313, 15 September 2014, pp. 60-66.
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