Home > Press > New Advancement in Targeted Gene Delivery to Cancerous Cells
Abstract:
Iranian researchers from Mashhad University of Technology in association with their counterparts from Rutgers University in the US produced peptide carriers to be used in targeted gene delivery to breast cancer cells.
New Advancement in Targeted Gene Delivery to Cancerous Cells
Tehran, Iran | Posted on October 22nd, 2013 The carriers have biological base and are able to compress genes to nanometric scale, and they can be used in the treatment of cancers, including breast cancer.
Gene therapy is one of the methods to treat various diseases, which has recently attracted the attention of scientists. Effective and true delivery of gene to the target tissue is the most important part of this treatment, which has always been a challenge in this method. A good carrier should compress DNA at micron scale to a nanoparticle so that the particle will be adsorbed by cell membrane through endocytosis.
In-vitro analysis showed that the newly-produced carrier could successfully pass through all cellular blocks and it successfully delivered luciferase gene to the core of AR-75-1 cells. Among other advantages of these biological carriers, mention can be made of their low toxicity in comparison with virus carriers and chemical and polymeric kinetics carriers.
Dr. Fatemeh Soltani, one of the Iranian researchers, explained about the plan, and said, "By obtaining recombinant peptides of the newly produced carrier with biological source and high performance, it can be expected that the product would take the place of virus carriers in the future to transfer gene in gene therapy process in the treatment of various diseases."
Some results of the research have been published in January 2013 in International Journal of Pharmaceutics, vol. 441, pp. 307-315.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Closing the gaps — MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Nanomedicine
Multiphoton polymerization: A promising technology for precision medicine February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
SMART researchers pioneer first-of-its-kind nanosensor for real-time iron detection in plants February 28th, 2025
Discoveries
Closing the gaps — MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Announcements
Closing the gaps — MXene-coating filters can enhance performance and reusability February 28th, 2025
Rice researchers harness gravity to create low-cost device for rapid cell analysis February 28th, 2025
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Leading the charge to better batteries February 28th, 2025
Quantum interference in molecule-surface collisions February 28th, 2025
New ocelot chip makes strides in quantum computing: Based on "cat qubits," the technology provides a new way to reduce quantum errors February 28th, 2025
Research partnerships
SMART researchers pioneer first-of-its-kind nanosensor for real-time iron detection in plants February 28th, 2025
Gene therapy relieves back pain, repairs damaged disc in mice: Study suggests nanocarriers loaded with DNA could replace opioids May 17th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Researchers’ approach may protect quantum computers from attacks March 8th, 2024
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||