Home > Press > Iranian Scientists Produce New DNA Genosensor
Abstract:
Iranian researchers from Mazandaran University introduced a new DNA genosensor by synthesizing gold nanoparticles through chemical reduction method and producing carbon paste electrodes modified with the synthesized gold nanoparticles.
Iranian Scientists Produce New DNA Genosensor
Tehran, Iran | Posted on September 16th, 2013 The results of the research can be used in pharmaceutical and medical industries, diagnosis of genetic malfunctions, and clinical diagnosis in hospitals and clinics.
Seyedeh Zeinab Moussavi Sani, one of the researchers of the plan, elaborated on the research, and said, "The use of gold nanoparticles in the structure of carbon paste increases the conductivity and the amount of the stabilized target DNA on the surface of the modified electrode. It also increases the electrochemical signal of guanine oxidation on the surface of the carbon paste electrode modified with gold nanoparticles in comparison with the bare carbon paste electrode. It finally results in an increase in the selectivity of the biosensor towards the target DNA and the sensitivity of the method."
Results showed that the produced biosensors had more desirable selectivity in DNA crossing than complementary DNA in comparison with non-complementary DNA series.
"The comparison between the values obtained for the linear range of concentration and detection limit on the surface of biosensors made of bare carbon paste electrodes and carbon paste electrodes modified with gold nanoparticles showed that carbon paste electrodes modified with gold nanoparticles had a wider concentration linear range while they had smaller detection limit. Therefore, we increased the sensitivity of the biosensor by using gold nanoparticles in the structure of carbon paste electrode. Taking into account that DNA concentration is very low at biological media, the production of biosensors that are able to measure low concentrations of DNA is very important," Moussavi said.
Results of the research have been published on 10 June 2013 in Journal of Chinese Chemical Society, vol. 60, issue 6. For more information about the details of the research, study the full article on pages 650-656 on the same journal.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Sensors innovations for smart lithium-based batteries: advancements, opportunities, and potential challenges August 8th, 2025
Deciphering local microstrain-induced optimization of asymmetric Fe single atomic sites for efficient oxygen reduction August 8th, 2025
Lab to industry: InSe wafer-scale breakthrough for future electronics August 8th, 2025
Nanomedicine
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
New imaging approach transforms study of bacterial biofilms August 8th, 2025
Cambridge chemists discover simple way to build bigger molecules – one carbon at a time June 6th, 2025
Electrifying results shed light on graphene foam as a potential material for lab grown cartilage June 6th, 2025
Discoveries
Deciphering local microstrain-induced optimization of asymmetric Fe single atomic sites for efficient oxygen reduction August 8th, 2025
ICFO researchers overcome long-standing bottleneck in single photon detection with twisted 2D materials August 8th, 2025
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
Simple algorithm paired with standard imaging tool could predict failure in lithium metal batteries August 8th, 2025
Announcements
Sensors innovations for smart lithium-based batteries: advancements, opportunities, and potential challenges August 8th, 2025
Deciphering local microstrain-induced optimization of asymmetric Fe single atomic sites for efficient oxygen reduction August 8th, 2025
Japan launches fully domestically produced quantum computer: Expo visitors to experience quantum computing firsthand August 8th, 2025
ICFO researchers overcome long-standing bottleneck in single photon detection with twisted 2D materials August 8th, 2025
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
Simple algorithm paired with standard imaging tool could predict failure in lithium metal batteries August 8th, 2025
First real-time observation of two-dimensional melting process: Researchers at Mainz University unveil new insights into magnetic vortex structures August 8th, 2025
Lab to industry: InSe wafer-scale breakthrough for future electronics August 8th, 2025
Nanobiotechnology
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
New imaging approach transforms study of bacterial biofilms August 8th, 2025
Ben-Gurion University of the Negev researchers several steps closer to harnessing patient's own T-cells to fight off cancer June 6th, 2025
Electrifying results shed light on graphene foam as a potential material for lab grown cartilage June 6th, 2025
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||