Home > Press > Tracking Gold Nanoparticles in the Body: Where Do They Go?
 |
Abstract:
Ivan M. Kempson et al. have investigated the intravenous delivery and excretion of polyethylene glycol (PEG)-coated gold nanoparticles (GNPs) in the whiskers and at the pilosebaceous unit in a mouse model. The use of X-ray fluorescence allowed visualisation of this deposition and, after 14 days, gold bands could be visualised in the hairs, the pharmacokinetic profiles of which indicated the blood concentration kinetics.
Tracking Gold Nanoparticles in the Body: Where Do They Go?
Germany | Posted on November 19th, 2012This deposition of nanoparticles was found to take place intermittently during this 14 day period, so demonstrating the prolonged mobility of these nanoparticles within the body. Furthermore, confocal microscopy was used to make a 3D reconstruction of nanoparticle distribution leading to identification of nanoparticle aggregates within the medullary canal.
These results are of interest in understanding the fate and excretion of nanoparticles from the body. Also, due to the successful elucidation of kinetic information from hair samples, this illustrates the potential for testing the nanoparticle load in the body via hair sampling as oppose to blood sampling.
####
For more information, please click here
Copyright © Wiley-VCH Materials Science Journals
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related Links |
Link to the original paper on Wiley Online Library:
| Related News Press |
News and information
Researchers develop molecular qubits that communicate at telecom frequencies October 3rd, 2025
Next-generation quantum communication October 3rd, 2025
"Nanoreactor" cage uses visible light for catalytic and ultra-selective cross-cycloadditions October 3rd, 2025
Nanomedicine
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
New imaging approach transforms study of bacterial biofilms August 8th, 2025
Cambridge chemists discover simple way to build bigger molecules – one carbon at a time June 6th, 2025
Electrifying results shed light on graphene foam as a potential material for lab grown cartilage June 6th, 2025
Discoveries
Researchers develop molecular qubits that communicate at telecom frequencies October 3rd, 2025
Next-generation quantum communication October 3rd, 2025
"Nanoreactor" cage uses visible light for catalytic and ultra-selective cross-cycloadditions October 3rd, 2025
Announcements
Rice membrane extracts lithium from brines with greater speed, less waste October 3rd, 2025
Researchers develop molecular qubits that communicate at telecom frequencies October 3rd, 2025
Next-generation quantum communication October 3rd, 2025
"Nanoreactor" cage uses visible light for catalytic and ultra-selective cross-cycloadditions October 3rd, 2025
Safety-Nanoparticles/Risk management
Onion-like nanoparticles found in aircraft exhaust May 14th, 2025
Closing the gaps — MXene-coating filters can enhance performance and reusability February 28th, 2025
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||