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Mitos electrophoresis chip

Abstract:
The Mitos capillary electrophoresis chip A separates species on their size to charge ratio

Dolomite Microfluidic Glass Chip Separates Biological Molecules

Royston, UK | Posted on July 15th, 2009

Dolomite, a world leader in microfluidic design and manufacture, has introduced the glass Mitos Capillary Electrophoresis Chip A to separate small quantities of biological molecules by capillary electrophoresis. Measuring only 15 x 45 x 2 mm, this electrophoresis chip combines a cross channel design with a 20 µm channel depth and a 30 mm long channel for accurate analysis of the separation.

With excellent chemical compatibility, the Mitos Capillary Electrophoresis Chip A separates species in the interior of the microchannel based on their size to charge ratio. The high surface to volume ratio of the microchannels enables the application of high voltages without overheating the samples. Furthermore, an extremely smooth channel surface, in combination with a wide pressure and temperature range make it ideal for a broad range of applications.

Dolomite also allows users to custom design chips with straight channels up to 150 mm in length, for improved detection sensitivity. Furthermore, the electrophoresis chip can be fabricated with a channel depth varying from 250 nm to 300 µm, allowing accurate analysis of different sample volumes. The thickness of the top and base layers can range from 150 µm to 5 mm, and the
entire chip can be fabricated from quartz, if required. With excellent optical transmission and high visibility, this chip allows excellent access for microscope-based inspection systems.

For further information on the Mitos Capillary Electrophoresis Chip A as well as the full range of microfluidic capabilities available from Dolomite including pumps, interconnects, chips and valves, please visit www.dolomite-microfluidics.com.

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About Dolomite
Dolomite is a global leader in the design and manufacture of microfluidics devices. With offices in the UK, US and Japan and distributors throughout the rest of the world, its clients range from universities developing leading-edge analytical equipment, to manufacturers of chemical, life sciences and clinical diagnostics systems.

Excellent microfabrication facilities that include cleanrooms, precision glass processing facilities and applications laboratories were established with Ł2m in funding from the UK Department of Trade and Industry's Micro and Nano Technology (MNT) Manufacturing Initiative. Dolomite’s expertise includes top quality engineering and scientific staff with strong backgrounds across the broad range of disciplines required for success in bringing microfluidics applications to the market, including chemistry, biotechnology, control system development, electronics, physics and instrument design and supply.

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