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June 1st, 2009
Nano cancer killers
Abstract:
Carbon nanotubes can allow Raman spectroscopy to be used as a technique for real-time detecting, tracking, and, with laser assistance, even killing cancer cells, according to researchers in the US.
The discovery could open up a new, battle front in the fight against cancer with the promise of a new generation of therapeutic agents beyond surgery, radiation, and conventional anticancer chemotherapy drugs.
Alex Biris of the University of Arkansas at Little Rock (UALR) is chief scientist at the Nanotechnology Center and is working with colleague in the medical sciences Vladimir Zharov, to develop the technique. They report details of their efforts in the latest issue of the Journal of Biomedical Optics.
"Until now, nobody has been able to fully understand and study in vivo and in real time how these nanoparticles travel through a living system," Biris said. "By using Raman spectroscopy, we showed that it is possible not only to monitor and detect nanomaterials moving through the circulation, but also to detect single cancer cells tagged with carbon nanotubes. In this way, we can measure their clearance rate and their biodistribution kinetics through the lymph and blood systems."
Source:
spectroscopynow.com
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