Home > Press > Zetasizer Nano contributes to drug carrier research at UK’s newest School of Pharmacy
Abstract:
Nanoparticle characterization using the Zetasizer Nano from Malvern Instruments is providing essential information for researchers working on drug delivery systems at the UK's newest School of Pharmacy and Pharmaceutical Sciences. The new school, which opened in September 2007, is part of the University of Central Lancashire.
Nanoparticle characterization using the Zetasizer Nano from Malvern Instruments is providing essential information for researchers working on drug delivery systems at the UK's newest School of Pharmacy and Pharmaceutical Sciences. The new school, which opened in September 2007, is part of the University of Central Lancashire. It is developing a multi-disciplinary approach to research, focusing on important areas of pharmaceutical sciences and practice. One such is pharmaceutics and pharmaceutical analysis where research teams are working with a range of colloidal systems for drug delivery, including microspheres, aerosols and dendrimers.
Prof. Antony D'Emanuele, Chair in Pharmaceutics and Head of the School, leads the Dendrimer Group, whose work centres on the development of nanocarriers for a number of pharmaceutical and biomedical applications. Dendrimers are well-defined and effectively monodisperse, highly branched molecules possessing an architecture that allows control over properties such as shape, size, density, polarity, reactivity and solubility. Their surface groups are amenable to modification and can be tailored for specific applications.
"As part of our work we are developing a range of nanocarriers for oral drug delivery," said Prof. D'Emanuele. "It is here that the Zetasizer Nano has proved especially useful in allowing us to characterize surface engineered dendrimers intended for this purpose. We are able to monitor changes in size as we modify the surface of our dendrimers and also determine whether our carriers aggregate."
The Zetasizer Nano simplifies the automated measurement of particle size, stability characterization using zeta potential, and molecular weight, for a wide range of dispersions, emulsions and molecules in solution. Sensitive enough for the measurement of solutions of proteins and polymers, yet able to measure at high concentrations, it is now the method of choice for nano-particle applications from routine colloid size measurement to the investigation of particulates at the leading edge of materials research.
Particle size measurement is in the range 0.6 to 6000 nm, molecular weight measurement from 1 x 103 to 2 x 107 Daltons, and zeta potential of particles from 5 nm to 10 µm.
The new School has a suite of particle sizing equipment which also includes Malvern Spraytec and Mastersizer systems.www.malvern.com
Malvern, Malvern Instruments, Zetasizer and Mastersizer are registered trademarks of Malvern Instruments Ltd Spraytec is a trademark of Malvern Instruments Ltd
High resolution image attached or available from Trish Appleton, Kapler Communications Ref: MAL/JOB/1420
####
About Malvern Instruments
Malvern Instruments provides a range of complementary materials characterization tools that deliver inter-related measurements reflecting the complexities of particulates and disperse systems, nanomaterials and macromolecules. Analytical instruments from Malvern are used in the characterization of a wide variety of materials, from industrial bulk powders to the latest nanomaterials and delicate macromolecules. A broad portfolio of innovative technologies is combined with intelligent, user-friendly software. These systems deliver industrially relevant data enabling our customers to make the connection between micro (such as particle size) and macro (bulk) material properties (rheology) and chemical composition (chemical imaging).
Particle size distribution, particle shape information, zeta potential, molecular weight, chemical composition, and bulk materials properties can all be determined with instruments from the Malvern range. The company’s laboratory, at-line, on-line and in-line solutions are proven in sectors as diverse as cement production and pharmaceutical drug discovery.
Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Korea and Japan, a joint venture in India, a global distributor network and applications laboratories around the world. www.malvern.com
Contacts:
Trish Appleton
Kapler Communications
Knowledge Centre
Wyboston Lakes
Great North Road,
Wyboston
Bedfordshire
MK44 3BY
UK
T: +44 (0)1480 479280;
F: +44 (0)1480 470343
USA contact:
Marisa Fraser
Malvern Instruments Inc
117 Flanders Road
Westborough
MA 01581-1042
USA
Tel: +1 508 768 6400
Fax: +1 508 768 6403
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related News Press |
News and information
Beyond wires: Bubble technology powers next-generation electronics:New laser-based bubble printing technique creates ultra-flexible liquid metal circuits November 8th, 2024
Nanoparticle bursts over the Amazon rainforest: Rainfall induces bursts of natural nanoparticles that can form clouds and further precipitation over the Amazon rainforest November 8th, 2024
Nanotechnology: Flexible biosensors with modular design November 8th, 2024
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Nanomedicine
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Unveiling the power of hot carriers in plasmonic nanostructures August 16th, 2024
Announcements
Nanotechnology: Flexible biosensors with modular design November 8th, 2024
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Turning up the signal November 8th, 2024
Nanofibrous metal oxide semiconductor for sensory face November 8th, 2024
Tools
Turning up the signal November 8th, 2024
Quantum researchers cause controlled ‘wobble’ in the nucleus of a single atom September 13th, 2024
Faster than one pixel at a time – new imaging method for neutral atomic beam microscopes developed by Swansea researchers August 16th, 2024
The latest news from around the world, FREE | ||
Premium Products | ||
Only the news you want to read!
Learn More |
||
Full-service, expert consulting
Learn More |
||