Nanotechnology Now - Press Release: VITROCELLŽ SYSTEMS finds during EUROTOX 2007 growing interest in its in vitro cultivation and exposure systems for the analysis of the effects of nano

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VITROCELLŽ cultivation module for the exposure to nano particles

Abstract:
The 44th Congress of the European Societies of Toxicology was held in Amsterdam, the Netherlands and closed yesterday on 10. October 2007.

VITROCELLŽ SYSTEMS finds during EUROTOX 2007 growing interest in its in vitro cultivation and exposure systems for the analysis of the effects of nano

Amsterdam, Netherlands | Posted on October 11th, 2007

More than 700 scientific presentations were held on various topics such as the newest developments in toxicogenomics, alternatives for animals testing, risk assessment, immunotoxicity, reproductive toxicity, environmental toxicity, genotoxicity and carcino-genesis, endocrine disruption, molecular toxicology, signal transduction, the risks of nanotechnology, REACH and idiosyncratic effects.

VITROCELLŽ SYSTEMS participated in the exhibition and presented its broad product program of equipment for the in vitro analysis of airborne substances such as gases, nano particles and complex mixtures. Key interest was shown in the VITROCELLŽ technology for the exposure of lung epithelial cells to nano materials at the air/liquid interface. Frequently these materials are just added to the cell culture medium which is - according to VITROCELLŽ SYSTEMS - a method giving relatively low sensitivity due to interaction of the particles with the medium. In using the VITROCELLŽ direct exposure technology, the cells are first cultivated on membrane inserts (e. g. ThinCertsŽ from Greiner, CostarŽ from Corning or FalconŽ from Becton Dickenson). The membrane inserts are placed in the VITROCELLŽ modules which are tempered at 37°C. The medium supply is performed either static or by permanent exchange so that the cells receive the cell culture medium from below through the membrane of the insert. The special aerosol inlets of the module are from stainless steel with a PFA-based surface treatment and deliver the particles to the cells by a low vacuum flow. As the cells are not covered with medium, they are exposed in the most efficient way at air/liquid interface. The same technological approach can be applied also to bacteria.

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About VITROCELLŽ SYSTEMS
VITROCELLŽ SYSTEMS supplies in addition the required aerosol generators as well as turnkey installations. The customers of VITROCELLŽ SYSTEMS are leading medical and environmental research institutes as well as the pharmaceutical and other industries.

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Contacts:
Tobias Krebs
Phone: +49 172 60 40 370

Ansprechpartner:

Herr Tobias Krebs
E-Mail:
Telefon: +49 (7681) 24-100
Fax: +49 (7681) 43-54

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