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October 19th, 2006

HYPER-CEST MRI Breaks New Ground in Molecular Imaging

Abstract:
Researchers with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley have developed a new technique for Magnetic Resonance Imaging (MRI) that allows detection of signals from molecules present at 10,000 times lower concentrations than conventional MRI techniques. Called HYPER-CEST, for hyperpolarized xenon chemical exchange saturation transfer, this new technique holds great promise for molecular imaging, in which the spatial distribution of specific molecules is detected within an organism. Ultimately, HYPER-CEST could become a valuable tool for medical diagnosis, including the early detection of cancer.

Source:
Berkeley Lab

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