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August 11th, 2006

PALM technique points to protein whereabouts

Abstract:
Researchers at the Howard Hughes Medical Institute, New Millennium Research, National Institute of Child Health and Human Development, Florida State University, and NuQuest Research, all in the US, have come up with an optical imaging technique that can pinpoint proteins in cells with nanometre resolution. The method, dubbed photoactivated localization microscopy (PALM) attaches fluorescent protein molecules to the proteins of interest and photoactivates, and images just a few of the fluorescent molecules at a time.

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