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January 18th, 2006

One-Pot Route To Nanocontainer

Abstract:
In a stroke of serendipity, chemists at Rutgers University have discovered a one-pot reaction in which 18 molecular components react sequentially to form, in high yield, a cavernous, covalent molecule that potentially could encapsulate other, smaller molecules.

Although a couple of covalent "nanocontainer" molecules have been synthesized previously, the new route is operationally far more efficient, and it also is atom-efficient. These features could be advantageous in potential applications such as drug delivery, separation science, catalysis, and sensing.

Source:
Chemical & Engineering News

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