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November 20th, 2003

Fishing for proteins

Abstract:
Metal nanoparticles can be used as selective probes in biochemical assays that screen the interactions of proteins and other molecules, thanks to a method developed by US researchers. Assays like this could be useful for drug discovery and for proteomics. Chad Mirkin and co-workers at Northwestern University in Evanston, Illinois, have made chemically modified gold nanoparticles that bind discriminatingly to proteins and signal this binding event both visually and spectroscopically.

Source:
* Nature

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